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Bioinformatics, HPC

Phylogenomics and molecular taxonomy generate enormous amounts of data through the use of new sequencing techniques, which pose completely new challenges for data analyses and data security.
Within the zmb, we are meeting these challenges by developing new algorithms and programs and operating a high-performance computer.

The bioinformatics, biodiversity informatics, and IT sections work closely together at the LIB.

In addition, they support the scientists at the entire LIB with their expertise. Dr Alexander Donath (bioinformatician) and Mr Sebastian Martin (scientific programmer) are currently based in the section.

Contact person

Dr. Alexander Donath

  • Head of Section
  • Head of HPC units

Phone: +49 228 9122 344
E-Mail: a.donath@leibniz-lib.de

Projects

Publications

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    2025

  • 2025/3

    Möhring, J., Hüllen, S., Martin, S., Mokodongan, D.F., Wowor, D., Schwarzer, J., Herder, F.

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    Increased phenotypic diversity as a consequence of ecological opportunity in the island radiation of Sulawesi ricefishes (Teleostei: Adrianichthyidae)

    BMC Ecology and Evolution, 1, 25

  • 2025/1

    Oriowo, T.O., Chrysostomakis, I., Martin, S., Kukowka, S., Brown, T., Winkler, S., Myers, E.W., Boehne, A., Stange, M.

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    A chromosome-level, haplotype-resolved genome assembly and annotation for the Eurasian minnow (Leuciscidae: Phoxinus phoxinus) provide evidence of haplotype diversity

    Gigascience, 14

  • 2025/1

    Mozer, A., Di‐Nizo, C.B., Consul, A., Huettel, B., Jäger, R., Akintayo, A., Erhardt, C., Fenner, L., Fischer, D., Forat, S., Gimnich, F., Grobe, P., Martin, S., Nathan, V., Saeed, A., von der Mark, L., Woehle, C., Olek, K., Misof, B., Astrin, J.J.

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    FOGS: A SNPSTR Marker Database to Combat Wildlife Trafficking and a Cell Culture Bank for Ex‐Situ Conservation

    Molecular Ecology resources

  • 2024

  • 2024/11

    Bakker, T.C.M., Hiermes, M., Müller, B., Martin, S., Rennison, D.J., Rick, I.P.

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    Adaptive variation in opsin expression of sticklebacks from different photic habitats

    Hydrobiologia

  • 2024/8

    Hofmann, S., Rödder, D., Andermann, T., Matschiner, M., Riedel, J., Baniya, C.B., Flecks, M., Yang, J., Jiang, K., Jianping, J., Litvinchuk, S.N., Martin, S., Masroor, R., Nothnagel, M., Vershinin, V., Zheng, Y., Jablonski, D., Schmidt, J., Podsiadlowski, L.

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    Exploring Paleogene Tibet's warm temperate environments through target enrichment and phylogenetic niche modelling of Himalayan spiny frogs (Paini, Dicroglossidae)

    Molecular ecology, 15, 33

  • 2024/8

    Hofmann, S., Podsiadlowski, L., Andermann, T., Matschiner, M., Baniya, C.B., Litvinchuk, S.N., Martin, S., Masroor, R., Yang, J., Zheng, Y., Jablonski, D., Schmidt, J.

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    The last of their kind: Is the genus Scutiger (Anura: Megophryidae) a relict element of the paleo-transhimalaya biota?

    Molecular Phylogenetics and Evolution

  • 2024/7

    Frandsen, P.B., Holzenthal, R.W., Espeland, M., Breinholt, J., Thomas Thorpe, J.A., Simon, S., Kawahara, A.Y., Plotkin, D., Hotaling, S., Li, Y., Nelson, C.R., Niehuis, O., Mayer, C., Podsiadlowski, L., Donath, A., Misof, B., Moriarty Lemmon, E., Lemmon, A., Morse, J.C., Liu, S., Pauls, S.U., Zhou, X.

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    Phylogenomics recovers multiple origins of portable case making in caddisflies (Insecta: Trichoptera), nature’s underwater architects

    Proceedings - Royal Society. Biological sciences/Proceedings - Royal Society. Biological Sciences, 2026, 291

  • 2023

  • 2023/12

    Böhne, A., Oğuzhan, Z., Chrysostomakis, I., Vitt, S., Meuthen, D., Martin, S., Kukowka, S., Thünken, T.

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    Evidence for selfing in a vertebrate from whole-genome sequencing

    Genome Research, 12, 33

  • 2023/8

    Flury, J.M., Meusemann, K., Martin, S., Hilgers, L., Spanke, T., Böhne, A., Herder, F., Mokodongan, D.F., Altmüller, J., Wowor, D., Misof, B., Nolte, A.W., Schwarzer, J.

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    Potential contribution of ancient introgression to the evolution of a derived reproductive strategy in ricefishes

    Genome biology and evolution, 8, 15

  • 2023/7

    Frankenbach, S., Melo Clavijo, J., Brück, M., Bleidißel, S., Simon, M., Gasparoni, G., Lo Porto, C., Laetz, E.M.J., Greve, C., Donath, A., Pütz, L., Sickinger, C., Serôdio, J., Christa, G.

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    Shedding light on starvation in darkness in the plastid-bearing sea slug Elysia viridis (Montagu, 1804)

    Marine biology, 7, 170

  • 2023/2

    Moris, V.C., Podsiadłowski, L., Martín, S., Oeyen, J.P., Donath, A., Petersen, M., Wilbrandt, J., Misof, B., Liedtke, D., Thamm, M., Scheiner, R., Schmitt, T., Niehuis, O.

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    Intrasexual cuticular hydrocarbon dimorphism in a wasp sheds light on hydrocarbon biosynthesis genes in Hymenoptera

    1, 6

  • 2022

  • 2022/6

    Joshi, M., Espeland, M., Dincă, V., Vila, R., Tahami, M.S., Dietz, L., Mayer, C., Martin, S., Dapporto, L., Mutanen, M.

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    Delimiting continuity: Comparison of target enrichment and double digest restriction‐site associated DNA sequencing for delineating admixing parapatric Melitaea butterflies

    Systematic entomology, 4, 47

  • 2022/1

    Rola, M., Frankenbach, S., Bleidissel, S., Sickinger, C., Donath, A., Frommlet, J.C., Greve, C., Serôdio, J., Preisfeld, A., Melo Clavijo, J., Christa, G.

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    Cladobranchia (Gastropoda, Nudibranchia) as a Promising Model to Understand the Molecular Evolution of Photosymbiosis in Animals

    Frontiers in Marine Science, 8

  • 2021

  • 2021/12

    Karmeinski, D., Meusemann, K., Goodheart, J.A., Schroedl, M., Martynov, A., Korshunova, T., Wägele, H., Donath, A.

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    Transcriptomics provides a robust framework for the relationships of the major clades of cladobranch sea slugs (Mollusca, Gastropoda, Heterobranchia), but fails to resolve the …

    BMC ecology and evolution, 21

  • 2021/11

    Kohli, M.K., Letsch, H., Greve, C., Béthoux, O., Deregnaucourt, I., Liu, S., Zhou, X., Donath, A., Mayer, C., Podsiadłowski, L., Gunkel, S., Machida, R., Niehuis, O., Rust, J., Wappler, T., Xin, Y., Misof, B., Ware, J.L.

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    Evolutionary history and divergence times of Odonata (dragonflies and damselflies) revealed through transcriptomics

    iScience, 11, 24

  • 2021/10

    Vasilikopoulos, A., Balke, M., Kukowka, S., Pflug, J.M., Martin, S., Meusemann, K., Hendrich, L., Mayer, C., Maddison, D.R., Niehuis, O., Beutel, R.G., Misof, B.

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    Phylogenomic analyses clarify the pattern of evolution of Adephaga (Coleoptera) and highlight phylogenetic artefacts due to model misspecification and excessive data trimming

    Systematic entomology, 4, 46

  • 2021/8

    Melo Clavijo, J., Drews, F., Pirritano, M., Simon, M., Salhab, A., Donath, A., Frankenbach, S., Serôdio, J., Bleidißel, S., Preisfeld, A., Christa, G.

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    The complete mitochondrial genome of the photosymbiotic sea slug Berghia stephanieae (Valdés, 2005) (Gastropoda, Nudibranchia)

    Mitochondrial DNA Part B, 8, 6

  • 2021/6

    Jasso-Martínez, J.M., Donath, A., Schulten, D., Zaldívar-Riverón, A., Sann, M.

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    Midgut transcriptome assessment of the cockroach-hunting wasp Ampulex compressa (Apoidea: Ampulicidae)

    PloS one, 6, 16

  • 2021/3

    Mayer, C., Dietz, L., Call, E., Kukowka, S., Martin, S., Espeland, M.

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    Adding leaves to the Lepidoptera tree: capturing hundreds of nuclear genes from old museum specimens

    Systematic entomology, 3, 46

  • 2021/2

    Bayless, K.M., Trautwein, M., Meusemann, K., Shin, S., Petersen, M., Donath, A., Podsiadłowski, L., Mayer, C., Niehuis, O., Peters, R.S., Meier, R., Kutty, S.N., Liu, S., Zhou, X., Misof, B., Yeates, D.K., Wiegmann, B.M.

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    Beyond Drosophila: resolving the rapid radiation of schizophoran flies with phylotranscriptomics

    BMC biology, 1, 19

  • 2021/1

    Paraskevopoulou, S., Käfer, S., Zirkel, F., Donath, A., Petersen, M., Liu, S., Zhou, X., Drosten, C., Misof, B., Junglen, S.

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    Viromics of extant insect orders unveil the evolution of the flavi-like superfamily

    Virus evolution, 1, 7

  • 2021/1

    Pauli, T., Meusemann, K., Kukowka, S., Sann, M., Donath, A., Mayer, C., Oeyen, J.P., Ballesteros, Y., Berg, A., van den Berghe, E., Escalona, H.E., Guglielmino, A., Niehuis, M., Fusu, L., Podsiadłowski, L., Polidori, C., de Rond, J., Rosa, P., Schmitt, T., Strumia, F., Wurdack, M., Liu, S., Zhou, X., Misof, B., Peters, R.S., Niehuis, O.

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    Analysis of RNA-Seq, DNA Target Enrichment, and Sanger Nucleotide Sequence Data Resolves Deep Splits in the Phylogeny of Cuckoo Wasps (Hymenoptera: Chrysididae)

    1, 5

  • 2020

  • 2020/12

    Szucsich, N.U., Bartel, D., Blanke, A., Böhm, A., Donath, A., Fukui, M., Grove, S., Liu, S., Macek, O., Machida, R., Misof, B., Nakagaki, Y., Podsiadlowski, L., Sekiya, K., Tomizuka, S., Reumont, B.M.V., Waterhouse, R.M., Walzl, M., Meng, G., Zhou, X., Pass, G., Meusemann, K.

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    Four myriapod relatives–but who are sisters? No end to debates on relationships among the four major myriapod subgroups

    BMC evolutionary biology, 20

  • 2020/11

    Meusemann, K., Trautwein, M., Friedrich, F., Beutel, R.G., Wiegmann, B.M., Donath, A., Podsiadlowski, L., Petersen, M., Niehuis, O., Mayer, C., Bayless, K.M., Shin, S., Liu, S., Hlinka, O., Minh, B.Q., Kozlov, A., Morel, B., Peters, R.S., Bartel, D., Grove, S., Zhou, X., Misof, B., Yeates, D.K.

    Show more...

    Are fleas highly modified Mecoptera? Phylogenomic resolution of Antliophora (Insecta: Holometabola)

  • 2020/11

    Song, H., Béthoux, O., Shin, S., Donath, A., Letsch, H., Liu, S., McKenna, D.D., Meng, G., Misof, B., Podsiadlowski, L., Zhou, X., Wipfler, B., Simon, S.

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    Author Correction: Phylogenomic analysis sheds light on the evolutionary pathways towards acoustic communication in Orthoptera

    Nature communications, 1, 11

  • 2020/10

    Song, H., Béthoux, O., Shin, S., Donath, A., Letsch, H., Liu, S., McKenna, D.D., Meng, G., Misof, B., Podsiadłowski, L., Zhou, X., Wipfler‍, B., Simon, S.

    Show more...

    Phylogenomic analysis sheds light on the evolutionary pathways towards acoustic communication in Orthoptera

    Nature communications, 1, 11

  • 2020/10

    Melo Clavijo, J., Frankenbach, S., Fidalgo, C., Serôdio, J., Donath, A., Preisfeld, A., Christa, G.

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    Identification of scavenger receptors and thrombospondin‐type‐1 repeat proteins potentially relevant for plastid recognition in Sacoglossa

    Ecology and Evolution, 21, 10

  • 2020/10

    Vasilikopoulos, A., Misof, B., Meusemann, K., Lieberz, D., Flouri, T., Beutel, R.G., Niehuis, O., Wappler, T., Rust, J., Peters, R.S., Donath, A., Podsiadlowski, L., Mayer, C., Bartel, D., Böhm, A., Liu, S., Kapli, P., Greve, C., Jepson, J.E., Liu, X., Zhou, X., Aspöck, H., Aspöck, U.

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    Correction to: An integrative phylogenomic approach to elucidate the evolutionary history and divergence times of Neuropterida (Insecta: Holometabola)

    BMC evolutionary biology, 1, 20

  • 2020/9

    Kowalski, P., Baum, M., Körten, M., Donath, A., Dobler, S.

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    ABCB transporters in a leaf beetle respond to sequestered plant toxins

    Proceedings - Royal Society. Biological sciences/Proceedings - Royal Society. Biological Sciences, 1934, 287

  • 2020/7

    Kohli, M., Letsch, H., Greve, C., Béthoux, O., Deregnaucourt, I., Liu, S., Zhou, X., Donath, A., Mayer, C., Podsiadlowski, L., Machida, R., Niehuis, O., Rust, J., Wappler, T., Yu, X., Misof, B., Ware, J.

    Show more...

    How old are dragonflies and damselflies? Odonata (Insecta) transcriptomics resolve familial relationships

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