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Dr. Madlen Stange

  • Head of Junior Research Group "Minnow"

Villa
Adenauerallee 160
53113 Bonn

Phone: +49 228 9122 367
E-Mail: m.stange@leibniz-lib.de

Profile

Research interests

In my working group we deal with population genomics (whole genome analyses), ecology and morphology of freshwater fish, currently with a focus on minnows(Phoxinus spp.). To this end, we carry out standardised monitoring by means of point abundance fishing, record ecological parameters, collect fish and examine them morphologically (geometric morphometry) and trophologically (stomach content analyses, stable isotopes). Finally, the results of the trophic and morphological investigations are combined with the results of the whole genome analyses in order to be able to make statements about species/population boundaries, ecological preferences of individual species and the influence of hybridisation through stocking measures. All genetic resources obtained are deposited in our biobank and the resulting data sets and analysis code are made available on open source databases.

Projects

Publications

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    2025

  • 2025/01

    Oriowo, T.O., Chrysostomakis, I., Martin, S., Kukowka, S., Brown, T., Winkler, S., Myers, E.W., Boehne, A., Stange, M.

    Show more...

    A chromosome-level, haplotype-resolved genome assembly and annotation for the Eurasian minnow (Leuciscidae: Phoxinus phoxinus) provide evidence of haplotype diversity

    Gigascience, 14

  • 2025/01

    Macphee, A., Oriowo, T.O., Sternberg, N., Stange, M.

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    Comparison of whole genome sequencing performance from fish swabs and fin clips

    BMC Research Notes, 1, 18

  • 2023

  • 2023/01

    Nadeau, S., Vaughan, T.G., Beckmann, C., Topolsky, I., Chen, C., Hodcroft, E.B., Schär, T., Nissen, I., Santacroce, N., Burcklen, E., Ferreira, P., Jablonski, K.P., Posada-Céspedes, S., Capece, V., Seidel, S., de Souza, N.S., Gómez, J.M.M., Cheng, P.F., Bosshard, P.P., Levesque, M.P., Kufner, V., Schmutz, S., Zaheri, M., Huber, M., Trkola, A., Cordey, S., Laubscher, F., Gonçalves, A.R., Aeby, S., Pillonel, T., Jacot, D., Bertelli, C., Greub, G., Leuzinger, K., Stange, M., Mari, A., Roloff, T., Seth-Smith, H.M.B., Hirsch, H.H., Egli, A., Redondo, M., Kobel, O., Noppen, C., du Plessis, L., Beerenwinkel, N., Neher, R.A., Beisel, C., Stadler, T.

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    Swiss public health measures associated with reduced SARS-CoV-2 transmission using genome data

    680, 15

  • 2022

  • 2022/01

    Brüningk, S.C., Klatt, J., Stange, M., Mari, A., Brunner, M., Roloff, T., Seth-Smith, H.M.B., Schweitzer, M., Leuzinger, K., Søgaard, K.K., Torres, D.A., Gensch, A., Schlotterbeck, A., Nickel, C.H., Ritz, N., Heininger, U., Bielicki, J., Rentsch, K., Fuchs, S., Bingisser, R., Siegemund, M., Pargger, H., Ciardo, D., Dubuis, O., Buser, A., Tschudin‐Sutter, S., Battegay, M., Schneider-Sliwa, R., Borgwardt, K., Hirsch, H.H., Egli, A.

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    Determinants of SARS-CoV-2 transmission to guide vaccination strategy in an urban area

    1, 8

  • 2022/01

    Wegner, F., Roloff, T., Huber, M., Cordey, S., Ramette, A., Gerth, Y., Bertelli, C., Stange, M., Seth-Smith, H.M.B., Mari, A., Leuzinger, K., Cerutti, L., Harshman, K., Xénarios, I., Le Mercier, P., Bittel, P., Neuenschwander, S., Opota, O., Fuchs, J., Panning, M., Michel, C., Hallin, M., Demuyser, T., De Mendonça, R., Savelkoul, P.H.M., Dingemans, J., van der Veer, B.M.J.W., Boers, S.A., Claas, E.C.J., Coolen, J.P.M., Melchers, W.J.G., Gunell, M., Kallonen, T., Vuorinen, T., Hakanen, A., Bernhoff, E., Hetland, M.A.K., Berman, H.G., Adar, S., Moran‐Gilad, J., Wolf, D.G., Leib, S.L., Nolte, O., Kaiser, L., Schmutz, S., Kufner, V., Zaheri, M., Trkola, A., Aamot, H.V., Hirsch, H.H., Greub, G., Egli, A.

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    External Quality Assessment of SARS-CoV-2 Sequencing: an ESGMD-SSM Pilot Trial across 15 European Laboratories

    1, 60

  • 2022/03

    Bishop, C.E., Gahm, K., Hendry, A.P., Jones, S.E., Stange, M., Solomon, C.T.

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    Benthic–limnetic morphological variation in fishes: Dissolved organic carbon concentration produces unexpected patterns

    3, 13

  • 2022/05

    Zürcher, K., Abela, I.A., Stange, M., Dupont, C., Mugglin, C., Egli, A., Trkola, A., Egger, M., Fenner, L.

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    Alpha Variant Coronavirus Outbreak in a Nursing Home Despite High Vaccination Coverage: Molecular, Epidemiological, and Immunological Studies

    4, 77

  • 2021

  • 2021/12

    Chen, C., Nadeau, S., Topolsky, I., Manceau, M., Huisman, J.S., Jablonski, K.P., Fuhrmann, L., Dreifuss, D., Jahn, K., Beckmann, C., Redondo, M., Noppen, C., Risch, L., Risch, M., Wohlwend, N., Kas, S., Bodmer, T., Roloff, T., Stange, M., Egli, A., Eckerle, I., Kaiser, L., Denes, R., Feldkamp, M., Nissen, I., Santacroce, N., Burcklen, E., Aquino, C., de Gouvea, A.C., Moccia, M., Grüter, S., Sykes, T., Opitz, L., White, G., Neff, L., Popovic, D., Patrignani, A., Tracy, J., Schlapbach, R., Dermitzakis, E.T., Harshman, K., Xénarios, I., Pegeot, H., Cerutti, L., Penet, D., Blin, A., Elies, M., Althaus, C.L., Beisel, C., Beerenwinkel, N., Ackermann, M., Stadler, T.

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    Quantification of the spread of SARS-CoV-2 variant B.1.1.7 in Switzerland

    37

  • 2021/03

    Stange, M., Mari, A., Roloff, T., Seth-Smith, H.M.B., Schweitzer, M., Brunner, M., Leuzinger, K., Søgaard, K.K., Gensch, A., Tschudin‐Sutter, S., Fuchs, S., Bielicki, J., Pargger, H., Siegemund, M., Nickel, C.H., Bingisser, R., Osthoff, M., Bassetti, S., Schneider-Sliwa, R., Battegay, M., Hirsch, H.H., Egli, A.

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    SARS-CoV-2 outbreak in a tri-national urban area is dominated by a B.1 lineage variant linked to a mass gathering event

    3, 17

  • 2021/01

    Fox, J.A., A, M.J., Stange, M.

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    Natural history study of an understudied sea catfish species from Panama (Siluriformes: Ariidae)

    4, 19

  • 2021/03

    Cabecinhas, A.R.G., Roloff, T., Stange, M., Bertelli, C., Huber, M., Ramette, A., Chen, C., Nadeau, S., Gerth, Y., Yerly, S., Opota, O., Pillonel, T., Schuster, T., Metzger, C., Sieber, J., Bel, M., Wohlwend, N., Baumann, C.R., Koch, M.C., Bittel, P., Leuzinger, K., Brunner, M., Suter‐Riniker, F., Berlinger, L., Søgaard, K.K., Beckmann, C., Noppen, C., Redondo, M., Steffen, I., Seth-Smith, H.M.B., Mari, A., Lienhard, R., Risch, M., Nolte, O., Eckerle, I., Lucchini, G.M., Hodcroft, E.B., Neher, R.A., Stadler, T., Hirsch, H.H., Leib, S.L., Risch, L., Kaiser, L., Trkola, A., Greub, G., Egli, A.

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    SARS-CoV-2 N501Y Introductions and Transmissions in Switzerland from Beginning of October 2020 to February 2021—Implementation of Swiss-Wide Diagnostic Screening and Whole Genome Sequencing

    4, 9

  • 2021/05

    Mari, A., Roloff, T., Stange, M., Søgaard, K.K., Asllanaj, E., Tauriello, G., Alexander, L.T., Schweitzer, M., Leuzinger, K., Gensch, A., Martinez, A.E., Bielicki, J., Pargger, H., Siegemund, M., Nickel, C.H., Bingisser, R., Osthoff, M., Bassetti, S., Sendi, P., Battegay, M., Marzolini, C., Seth-Smith, H.M.B., Schwede, T., Hirsch, H.H., Egli, A.

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    Global Genomic Analysis of SARS-CoV-2 RNA Dependent RNA Polymerase Evolution and Antiviral Drug Resistance

    5, 9

  • 2021/02

    Stange, M., Barrett, R.D.H., Hendry, A.P.

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    The importance of genomic variation for biodiversity, ecosystems and people

    Nature Reviews Genetics, 2, 22

  • 2019

  • 2019/09

    Heck, L., Sánchez‐Villagra, M.R., Stange, M.

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    Why the long face? Comparative shape analysis of miniature, pony, and other horse skulls reveals changes in ontogenetic growth

    7

  • 2018

  • 2018/01

    Stange, M., Sánchez‐Villagra, M.R., Salzburger, W., Matschiner, M.

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    Bayesian Divergence-Time Estimation with Genome-Wide Single-Nucleotide Polymorphism Data of Sea Catfishes (Ariidae) Supports Miocene Closure of the Panamanian Isthmus

    4, 67

  • 2018/08

    Stange, M., Núñez‐León, D., Sánchez‐Villagra, M.R., Jensen, P., Wilson, L.A.B.

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    Morphological variation under domestication: how variable are chickens?

    8, 5

  • 2018/03

    Stange, M., Aguirre‐Fernández, G., Salzburger, W., Sánchez‐Villagra, M.R.

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    Study of morphological variation of northern Neotropical Ariidae reveals conservatism despite macrohabitat transitions

    1, 18

  • 2018/04

    Heck, L., Wilson, L.A.B., Evin, A., Stange, M., Sánchez‐Villagra, M.R.

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    Shape variation and modularity of skull and teeth in domesticated horses and wild equids

    1, 15

  • 2016

  • 2016/07

    Stange, M., Aguirre‐Fernández, G., Cooke, R.G., Barros, T.R., Salzburger, W., Sánchez‐Villagra, M.R.

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    Evolution of opercle bone shape along a macrohabitat gradient: species identification using mtDNA and geometric morphometric analyses in neotropical sea catfishes (Ariidae)

    Ecology and Evolution, 16, 6

  • 2015

  • 2015/11

    Fuchs, M., Geiger, M., Stange, M., Sánchez‐Villagra, M.R.

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    Growth trajectories in the cave bear and its extant relatives: an examination of ontogenetic patterns in phylogeny

    1, 15

  • 2013

  • 2013/08

    Mateus, C.S., Stange, M., Berner, D., Roesti, M., Quintella, B.R., Alves, M.J., Almeida, P.R., Salzburger, W.

    Show more...

    Strong genome-wide divergence between sympatric European river and brook lampreys

    CB/Current biology, 15, 23

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