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Bioinformatics, HPC

Phylogenomics and molecular taxonomy generate enormous amounts of data through the use of new sequencing techniques, which pose completely new challenges for data analyses and data security.
Within the zmb, we are meeting these challenges by developing new algorithms and programs and operating a high-performance computer.

The bioinformatics, biodiversity informatics, and IT sections work closely together at the LIB.

In addition, they support the scientists at the entire LIB with their expertise. Dr Alexander Donath (bioinformatician) and Mr Sebastian Martin (scientific programmer) are currently based in the section.

Contact person

Dr. Alexander Donath

  • Head of Section
  • Head of HPC units

Phone: +49 228 9122 344
E-Mail: a.donath@leibniz-lib.de

Projects

Publications

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    2026

  • 2026/07

    Clarke, A.W., Bozek, L., Babalola, A.I., Wyrożemski, Ł., Paynter, V.M., Vinther, J., Donath, A., Olesen, J., Glenner, H., McPeek, M.A., Farrell, T.M., Fitak, R.R., Martinez, P., Fromm, B., Peterson, K.J.

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    Genomic Contingence Beneath Ecological Convergence: The Tempo and Mode of Gene Loss in Parasitic Bilaterians

    Evolution

  • 2026/02

    Postma, A., Klynsmith, L., Duong, T.A., Allison, J.D., Smidt, W., Waterhouse, R.M., Lesny, P., Oeyen, J.P., Petersen, M., Martin, S., Liu, S., Zhou, X., Ziesmann, T., Donath, A., Mayer, C., Misof, B., Niehuis, O., Peters, R.S., Podsiadlowski, L., Coetzee, M.P.A., Joubert, F., Slippers, B.

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    Genome and transcriptome‐based identification and expression profiling of chemosensory gene families across developmental stages and tissues in Sirex noctilio (Hymenoptera: Siricidae)

    Insect Molecular Biology

  • 2025

  • 2025/10

    Bleidorn, C., Sandberg, F., Martin, S., Vogler, A.P., Podsiadlowski, L.

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    The untapped potential of short-read sequencing in biodiversity research

    Trends in Genetics

  • 2025/05

    Letsch, H., Greve, C., Hundsdoerfer, A.K., Irisarri, I., Moore, J.M., Espeland, M., Wanke, S., Arifin, U., Blom, M.P.K., Corrales, C., Donath, A., Fritz, U., Köhler, G., Kück, P., Lemer, S., Mengual, X., Salas, N.M., Meusemann, K., Palandačić, A., Printzen, C., Sigwart, J.D., Silva-Brandão, K.L., Simões, M., Stange, M., Suh, A., Szucsich, N., Tilic, E., Töpfer, T., Böhne, A., Janke, A., Pauls, S.

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    Type genomics: a framework for integrating genomic data into biodiversity and taxonomic research

    Systematic Biology, 6, 74

  • 2025/03

    Möhring, J., Hüllen, S., Martin, S., Mokodongan, D.F., Wowor, D., Schwarzer, J., Herder, F.

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    Increased phenotypic diversity as a consequence of ecological opportunity in the island radiation of Sulawesi ricefishes (Teleostei: Adrianichthyidae)

    BMC Ecology and Evolution, 1, 25

  • 2025/01

    Mozer, A., Di‐Nizo, C.B., Consul, A., Huettel, B., Jäger, R., Akintayo, A., Erhardt, C., Fenner, L., Fischer, D., Forat, S., Gimnich, F., Grobe, P., Martin, S., Nathan, V., Saeed, A., von der Mark, L., Woehle, C., Olek, K., Misof, B., Astrin, J.J.

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    FOGS: A SNPSTR Marker Database to Combat Wildlife Trafficking and a Cell Culture Bank for Ex‐Situ Conservation

    Molecular Ecology resources

  • 2025/01

    Oriowo, T.O., Chrysostomakis, I., Martin, S., Kukowka, S., Brown, T., Winkler, S., Myers, E.W., Boehne, A., Stange, M.

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    A chromosome-level, haplotype-resolved genome assembly and annotation for the Eurasian minnow (Leuciscidae: Phoxinus phoxinus) provide evidence of haplotype diversity

    Gigascience, 14

  • 2024

  • 2024/11

    Bakker, T.C.M., Hiermes, M., Müller, B., Martin, S., Rennison, D.J., Rick, I.P.

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    Adaptive variation in opsin expression of sticklebacks from different photic habitats

    Hydrobiologia

  • 2024/08

    Hofmann, S., Podsiadlowski, L., Andermann, T., Matschiner, M., Baniya, C.B., Litvinchuk, S.N., Martin, S., Masroor, R., Yang, J., Zheng, Y., Jablonski, D., Schmidt, J.

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    The last of their kind: Is the genus Scutiger (Anura: Megophryidae) a relict element of the paleo-transhimalaya biota?

    Molecular Phylogenetics and Evolution

  • 2024/08

    Hofmann, S., Rödder, D., Andermann, T., Matschiner, M., Riedel, J., Baniya, C.B., Flecks, M., Yang, J., Jiang, K., Jianping, J., Litvinchuk, S.N., Martin, S., Masroor, R., Nothnagel, M., Vershinin, V., Zheng, Y., Jablonski, D., Schmidt, J., Podsiadlowski, L.

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    Exploring Paleogene Tibet's warm temperate environments through target enrichment and phylogenetic niche modelling of Himalayan spiny frogs (Paini, Dicroglossidae)

    Molecular ecology, 15, 33

  • 2024/07

    Frandsen, P.B., Holzenthal, R.W., Espeland, M., Breinholt, J., Thomas Thorpe, J.A., Simon, S., Kawahara, A.Y., Plotkin, D., Hotaling, S., Li, Y., Nelson, C.R., Niehuis, O., Mayer, C., Podsiadlowski, L., Donath, A., Misof, B., Moriarty Lemmon, E., Lemmon, A., Morse, J.C., Liu, S., Pauls, S.U., Zhou, X.

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    Phylogenomics recovers multiple origins of portable case making in caddisflies (Insecta: Trichoptera), nature’s underwater architects

    Proceedings - Royal Society. Biological sciences/Proceedings - Royal Society. Biological Sciences, 2026, 291

  • 2023

  • 2023/12

    Böhne, A., Oğuzhan, Z., Chrysostomakis, I., Vitt, S., Meuthen, D., Martin, S., Kukowka, S., Thünken, T.

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    Evidence for selfing in a vertebrate from whole-genome sequencing

    Genome Research, 12, 33

  • 2023/07

    Frankenbach, S., Melo Clavijo, J., Brück, M., Bleidißel, S., Simon, M., Gasparoni, G., Lo Porto, C., Laetz, E.M.J., Greve, C., Donath, A., Pütz, L., Sickinger, C., Serôdio, J., Christa, G.

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    Shedding light on starvation in darkness in the plastid-bearing sea slug Elysia viridis (Montagu, 1804)

    Marine biology, 7, 170

  • 2022

  • 2022/06

    Joshi, M., Espeland, M., Dincă, V., Vila, R., Tahami, M.S., Dietz, L., Mayer, C., Martin, S., Dapporto, L., Mutanen, M.

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    Delimiting continuity: Comparison of target enrichment and double digest restriction‐site associated DNA sequencing for delineating admixing parapatric Melitaea butterflies

    Systematic entomology, 4, 47

  • 2022/01

    Rola, M., Frankenbach, S., Bleidissel, S., Sickinger, C., Donath, A., Frommlet, J.C., Greve, C., Serôdio, J., Preisfeld, A., Melo Clavijo, J., Christa, G.

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    Cladobranchia (Gastropoda, Nudibranchia) as a Promising Model to Understand the Molecular Evolution of Photosymbiosis in Animals

    Frontiers in Marine Science, 8

  • 2021

  • 2021/08

    Melo Clavijo, J., Drews, F., Pirritano, M., Simon, M., Salhab, A., Donath, A., Frankenbach, S., Serôdio, J., Bleidißel, S., Preisfeld, A., Christa, G.

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    The complete mitochondrial genome of the photosymbiotic sea slug Berghia stephanieae (Valdés, 2005) (Gastropoda, Nudibranchia)

    Mitochondrial DNA Part B, 8, 6

  • 2021/06

    Jasso-Martínez, J.M., Donath, A., Schulten, D., Zaldívar-Riverón, A., Sann, M.

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    Midgut transcriptome assessment of the cockroach-hunting wasp Ampulex compressa (Apoidea: Ampulicidae)

    PloS one, 6, 16

  • 2020

  • 2020/11

    Song, H., Béthoux, O., Shin, S., Donath, A., Letsch, H., Liu, S., McKenna, D.D., Meng, G., Misof, B., Podsiadlowski, L., Zhou, X., Wipfler, B., Simon, S.

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    Author Correction: Phylogenomic analysis sheds light on the evolutionary pathways towards acoustic communication in Orthoptera

    Nature communications, 1, 11

  • 2020/11

    Meusemann, K., Trautwein, M., Friedrich, F., Beutel, R.G., Wiegmann, B.M., Donath, A., Podsiadlowski, L., Petersen, M., Niehuis, O., Mayer, C., Bayless, K.M., Shin, S., Liu, S., Hlinka, O., Minh, B.Q., Kozlov, A., Morel, B., Peters, R.S., Bartel, D., Grove, S., Zhou, X., Misof, B., Yeates, D.K.

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    Are fleas highly modified Mecoptera? Phylogenomic resolution of Antliophora (Insecta: Holometabola)

  • 2020/10

    Vasilikopoulos, A., Misof, B., Meusemann, K., Lieberz, D., Flouri, T., Beutel, R.G., Niehuis, O., Wappler, T., Rust, J., Peters, R.S., Donath, A., Podsiadlowski, L., Mayer, C., Bartel, D., Böhm, A., Liu, S., Kapli, P., Greve, C., Jepson, J.E., Liu, X., Zhou, X., Aspöck, H., Aspöck, U.

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    Correction to: An integrative phylogenomic approach to elucidate the evolutionary history and divergence times of Neuropterida (Insecta: Holometabola)

    BMC evolutionary biology, 1, 20

  • 2020/10

    Melo Clavijo, J., Frankenbach, S., Fidalgo, C., Serôdio, J., Donath, A., Preisfeld, A., Christa, G.

    Show more...

    Identification of scavenger receptors and thrombospondin‐type‐1 repeat proteins potentially relevant for plastid recognition in Sacoglossa

    Ecology and Evolution, 21, 10

  • 2020/07

    Kohli, M., Letsch, H., Greve, C., Béthoux, O., Deregnaucourt, I., Liu, S., Zhou, X., Donath, A., Mayer, C., Podsiadlowski, L., Machida, R., Niehuis, O., Rust, J., Wappler, T., Yu, X., Misof, B., Ware, J.

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    How old are dragonflies and damselflies? Odonata (Insecta) transcriptomics resolve familial relationships

  • 2020/01

    Wipfler, B., Koehler, W., Frandsen, P.B., Donath, A., Liu, S., Machida, R., Misof, B., Peters, R.S., Shimizu, S., Zhou, X., Simon, S.

    Show more...

    Phylogenomics changes our understanding about earwig evolution

    Systematic entomology, 3, 45

  • 2019

  • 2019/08

    Meinzer, F., Dobler, S., Donath, A., Lohr, J.N.

    Show more...

    Robust reference gene design and validation for expression studies in the large milkweed bug, Oncopeltus fasciatus, upon cardiac glycoside stress

    Gene, 710

  • 2018

  • 2018/12

    Donath, A., Stadler, P.F.

    Show more...

    Split-inducing indels in phylogenomic analysis

    Algorithms for Molecular Biology, 1, 13

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